About 20 vehicles were entered or broken into early Tuesday in Greenwood; and cash, laptops and other items were taken.
Most of the vehicles were left unlocked by the owner.
Valuable items, including laptops and a camera, were taken from some vehicles, while others were entered but nothing was taken.
The incidents occurred in three neighborhoods off Smith Valley Road, west of Averitt Road, and in an apartment complex near County Line Road and Madison Avenue.
Someone broke door handles and windows and damaged the vehicles to gain entry in the apartment complex. Most of the vehicles in the neighborhood were not damaged, and thieves entered unlocked vehicles.
The thefts could be related, but police are not sure if one or two groups are responsible, Police Chief Joe Pitcher said.
"It seems like everyone in the metro area is getting killed with these," Pitcher said.
Vehicles were broken into in Whiteland and Franklin over the weekend.
Police had more patrols out Wednesday night and encouraged people to lock their vehicles and not to leave valuables in them.
Greenwood police normally have four or five reports of theft from a vehicle each night, Pitcher said.
"This is obviously beyond what we are used to," he said.
A set of jumper cables was stolen from a vehicle in the 1200 block of Southbridge Drive. Someone entered the locked vehicle, damaging the door and prying open the glove box. In the same block, the window of a vehicle was damaged to allow access. A stereo was stolen from that vehicle.
A door handle was damaged and a stereo was stolen in a vehicle in the 300 block of Southbridge Drive.
A digital camera was stolen from an unlocked vehicle in the 800 block of Leatherwood Drive, and a DVD was stolen from a vehicle in the 500 block of Savannah Drive.
A laptop computer, portable TV and $550 in Target gift cards were stolen from a vehicle in the 700 block of Cypress South Drive; and $5 was stolen from a vehicle in the 800 block of Cypress South Drive.
A laptop computer, cell phone, briefcase, flashlight and $5 cash were stolen from a vehicle in the 400 block of Savannah Drive. Police believe the thief was scared off during the theft because the laptop was found down the street, Pitcher said.
Other reports said someone entered vehicles but nothing was taken.
By JENNIFER LEWIS